Pydio 8 + nginx + let's encrypt

Hello, i installed pydio 8 with Nginx following this tutorial

I would like to run it on 443 with ssl that I already generated with let’s encrypt, therefore I added those two lines in my nginx server config
ssl_certificate path/of/the/key/fullchain.pem;
ssl_certificate_key path/of/the/key/privkey.pem;
But it shows me ERR_CONNECTION_REFUSED, why is that?

Nb: i can’t connect on http (80) with the same nginx server config


Edit: Solved, thanks